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Diagnóstico da hepatite C na pratica medica: revisao da literatura

dc.contributor.authorBrandao, Ajacio Bandeira de Melloes_ES
dc.contributor.authorFuchs, Sandra Costaes_ES
dc.contributor.authorSilva, Mauro Alberto dos Anjoses_ES
dc.contributor.authorEmer, Leticia Fanckes_ES
dc.date.accessioned2015
dc.date.available2015
dc.date.issued2001es_ES
dc.identifier.citationBrandao, Ajacio Bandeira de Mello,Fuchs, Sandra Costa,Silva, Mauro Alberto dos Anjos,Emer, Leticia Fanck (2001) Diagnóstico da hepatite C na pratica medica: revisao da literatura. Rev Panam Salud Publica;9(3) 161-168,mar. 2001. Retrieved from http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892001000300005&lng=en&nrm=iso&tlng=ptes_ES
dc.identifier.urihttp://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892001000300005&lng=en&nrm=iso&tlng=ptes_ES
dc.identifier.urihttps://iris.paho.org/handle/10665.2/8605
dc.relation.ispartofseriesRev Panam Salud Publica;9(3),mar. 2001es_ES
dc.subjectHepatite Ces_ES
dc.subjectSorologiaes_ES
dc.subjectEnsaio de Imunoadsorção Enzimáticapt_BR
dc.subjectImmunoblottinges_ES
dc.subjectReação em Cadeia da Polimerasept_BR
dc.titleDiagnóstico da hepatite C na pratica medica: revisao da literaturaes_ES
dc.title.alternativeDiagnosing hepatitis C in clinical practice: a literature reviewes_ES
dc.typeJournal articlesen_US
dc.rights.holderPan American Health Organizationen_US
dc.description.notesThe objetive of this study was to review the literature concerning laboratory tests to detect hepatitis C virus infection, which have been available since 1989. The diagnosis of hepatitis C is mainly based on serological techniques and on molecular techniques. Serological techniques to detect hepatitis C virus antibodies are the method of choice to identify past or present infection. There are two types of serological assays highly sensitive enzyme-linked immunosorbent creening assays; and more specific immunoblot techniques, which are used as supplemental or confimartory tests. With respect to molecular diagnostic techniques, there are several types of assays. One such assay detects viral RNA. It is useful for diagnosis in such situations as the early stages of infection, with immunosuppressed patients, and with persons who have a low probability of infection. Molecular assays are also recommended before traetment with interferon and ribavirin, in order to monitor response to treatment. Other assays allow determination of viral load by either target amplification (as in polymerase chain reaction) or signal amplification (as in branched-DNA). Determining the hepatitis C virus genotype is possible using either molecular techniques or serotyping. Determining viral load and genotype is useful for planning the duration of interferon and ribavirin treatment. there have been major advances in the diagnosis of hepatitis C in the past decade improvements in the sensitivity and specificity of antibody tests have provided faster, less expensive diagnoses. however, more accurate assay are still needed for such groups as immunosuppressed persons and acute hepatitis patientsen_US


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