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dc.contributor.authorGarcía-Rivera, Enid Jes_ES
dc.contributor.authorRigau-Pérez, José Ges_ES
dc.date.accessioned2015-08-25T14:53:26Z
dc.date.available2015-08-25T14:53:26Z
dc.date.issued2003es_ES
dc.identifier.citationGarcía-Rivera, Enid J,Rigau-Pérez, José G (2003) Dengue severity in the elderly in Puerto Rico. Rev Panam Salud Publica;13(6) 362-368,jun. 2003. Retrieved from http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892003000500004&lng=pt&nrm=iso&tlng=enen_US
dc.identifier.urihttp://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892003000500004&lng=pt&nrm=iso&tlng=enes_ES
dc.identifier.urihttps://iris.paho.org/handle/10665.2/8430
dc.format.extenttabes_ES
dc.relation.ispartofseriesRev Panam Salud Publica;13(6),jun. 2003es_ES
dc.subjectDenguees_ES
dc.subjectVírus da Denguept_BR
dc.subjectDenguees_ES
dc.subjectVírus da Denguept_BR
dc.subjectPorto Ricoes_ES
dc.subjectAnálise de Regressãopt_BR
dc.subjectSorotipagemes_ES
dc.titleDengue severity in the elderly in Puerto Ricoen_US
dc.typeJournal articlesen_US
dc.rights.holderPan American Health Organizationen_US
dc.description.notesOBJECTIVE: Severe dengue affects all age groups in the Americas, but little detailed information is available about this disease in the elderly. The objective of this article is to describe the disease in this age group. METHODS: We reviewed suspected dengue-case investigation forms submitted with diagnostic samples as well as clinical reports from infection control nurses in Puerto Rico, for the period of 1994 through 1999. RESULTS: We assigned the laboratory-positive case-patients to four age groups: infants (1 year: 554), youth (2 to 18 years: 6 857), adults (19 to 64 years: 9 433), and elderly ( 65 years: 822). Regardless of infecting serotype, the elderly were more likely to have been hospitalized (48 percent vs. 33 percent) (P 0.01) and were less likely to show hemorrhage (26 percent vs. 33 percent) (P 0.01). On multivariate analysis, controlling for gender and the presence of hemorrhage, the elderly had a higher risk for hospitalization and death than did the youths and the adults. CONCLUSIONS: The elderly appear to be more likely than youth and younger adults to develop severe illness when infected with the dengue virus, in a pattern similar to that of infants. The clinical evaluation of elderly patients with dengue must include a careful assessment of increased capillary permeability and occult hemorrhage in order to avoid complications from delayed identification and treatment of severe dengue infection. These findings are of increasing importance for dengue epidemiology and medical care in view of the expanding nature of dengue and dengue hemorrhagic fever in a world that also has a growing number and proportion of elderly persons (AU)en_US


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