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Seroprevalence of dengue virus antibodies in asymptomatic Costa Rican children, 2002-2003: a pilot study

dc.contributor.authorIturrino-Monge, Robertoes_ES
dc.contributor.authorAvila-Agüero, Maria Les_ES
dc.contributor.authorAvila-Agüero, Claudio Res_ES
dc.contributor.authorMoya-Moya, Tatianaes_ES
dc.contributor.authorCañas-Coto, Alejandroes_ES
dc.contributor.authorCamacho-Badilla, Kattiaes_ES
dc.contributor.authorZambrano-Mora, Betzanaes_ES
dc.date.accessioned2015
dc.date.available2015
dc.date.issued2006es_ES
dc.identifier.citationIturrino-Monge, Roberto,Avila-Agüero, Maria L,Avila-Agüero, Claudio R,Moya-Moya, Tatiana,Cañas-Coto, Alejandro,Camacho-Badilla, Kattia,Zambrano-Mora, Betzana (2006) Seroprevalence of dengue virus antibodies in asymptomatic Costa Rican children, 2002-2003: a pilot study. Rev Panam Salud Publica;20(1) 39-43,jul. 2006. Retrieved from http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892006000700005es_ES
dc.identifier.urihttp://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892006000700005es_ES
dc.identifier.urihttps://iris.paho.org/handle/10665.2/7949
dc.format.extenttabes_ES
dc.relation.ispartofseriesRev Panam Salud Publica;20(1),jul. 2006es_ES
dc.subjectAnticorpos Antiviraises_ES
dc.subjectDengue Gravees_ES
dc.subjectDengue Gravees_ES
dc.subjectVírus da Denguept_BR
dc.subjectImunoglobulina Ges_ES
dc.subjectCosta Ricaes_ES
dc.subjectProjetos Pilotoes_ES
dc.subjectEstudos Prospectivospt_BR
dc.subjectEstudos Soroepidemiológicospt_BR
dc.titleSeroprevalence of dengue virus antibodies in asymptomatic Costa Rican children, 2002-2003: a pilot studyes_ES
dc.typeJournal articlesen_US
dc.rights.holderPan American Health Organizationen_US
dc.description.notesOBJECTIVES: Since 1993 dengue has become more frequent in Costa Rica. Adults have been the most affected population, while children have remained virtually unharmed. So far no studies have investigated how many asymptomatic children have been affected by this virus. This pilot study documents the seroprevalence, measured as the presence of IgG antibodies, of dengue virus in asymptomatic children from two different geographical areas. METHODS: This descriptive, prospective epidemiologic study compared the presence of antibodies in children who live in a coastal region of a tropical country where dengue is endemic, and an inland area where dengue is not endemic. An enzyme-linked immunosorbent assay was used to test the serum for dengue virus IgG antibodies. None of the children had a prior history of dengue, fever, immunosuppressive therapy or underlying disease. RESULTS: During the period from July 2002 to July 2003, 103 children were recruited from each area. In the costal region we found a seroprevalence of 36.9 percent. In the inland area seroprevalence was 2.9 percent CONCLUSIONS: We found a substantial number of asymptomatic infections in Costa Rican children. This greatly increases the risk of dengue hemorrhagic fever or dengue shock syndrome in these children, in whom previous dengue infection had gone undetected. Preventive efforts should be targeted at the costal region due to the higher prevalence in this area.(AU)en_US


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