Interpretation of laboratory results for COVID-19 diagnosis, 6 May 2020
MetadataShow full item record
Etiological confirmation of COVID-19 virus (SARS-CoV-2) infection can only be made by laboratory tests. In general, the currently available assays for COVID-19 can be classified into two groups: • The first group (virological tests) includes tests that can detect the presence of the components of the virus (genetic material or antigens). These tests can confirm the diagnosis of patients with symptoms compatible with COVID-19, detect infections in populations with high-risk of infection (such as health workers) or severity (hypertension, diabetes, obesity, cardiovascular history, chronic respiratory, immunosuppression, cancer, etc.), and assess whether an individual recovered from COVID-19 may still be infectious. • The second group of tests (serological) detects antibodies (IgM or IgG) generated as part of the individual's immune response against the SARS-CoV-2 virus, that is, they indicate previous or ongoing contact. The immunity (protection) conferred by the antibodies is still under investigation. Once sufficient evidence is available, serological tests would be, together with direct virus detection, an essential tool in the development of strategies that allow relaxation of current public health measures.
This notice should be preserved along with the article's original URL.Attribution-NonCommercial-ShareAlike 3.0 IGO
Showing items related by title, author, creator and subject.
Seroprevalence of anti-SARS-CoV-2 IgG in asymptomatic and pauci-symptomatic people over a 5 month survey in Argentina Rodeles, Luz María; Peverengo, Luz María; Benítez, Romina; Benzaquen, Nadia; Serravalle, Priscila; Long, Ana Karina; Ferreira, Virginia; Benitez, Agostina Daiana; Zunino, Luisina; Lizarraga, Camila; Vicco, Miguel Hernán (2021-06-15)[ABSTRACT]. Objective. To evaluate the seroprevalence of COVID-19 infection in pauci-symptomatic and asymptomatic people, the associated epidemiological factors, and IgG antibody kinetic over a 5-month period to get a ...
SARS-CoV-2 variants in severely symptomatic and deceased persons who had been vaccinated against COVID-19 in São Paulo, Brazil Rodrigues Campos, Karoline; Tavares Sacchi, Cláudio; Abbud, Adriano; Caterino-de-Araujo, Adele (2021-09-15)[ABSTRACT]. COVID-19 vaccination began in São Paulo, Brazil in January 2021, first targeting healthcare workers (HCWs) and the elderly, using the CoronaVac vaccine (Sinovac/Butantan) and subsequently the Oxford/AstraZeneca ...
Pan American Health Organization; Health Emergencies (PHE) (Washington, D.C., PAHO, 2020-03-30)Coronaviruses are a group of highly diverse RNA viruses in the Coronaviridae family that are divided in 4 genera: alpha, beta, gamma and delta that cause disease varying from mild to severe in human and animals (1-3). There ...