Foot-and-Mouth disease vaccines. I. Comparison of vaccines prepared from virus inactivated with formalin and adsorbed on aluminum hydroxide gel with saponin and virus inactivated with acetylethyleneimine and emulsified with incomplete Freund’s adjuvant
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[Introduction] A series of cooperative studies by PIADC and the Pan American Foot-and-Mouth Disease Center (PAFMDC) was undertaken in the isolation units at PAFMDC in Rio de Janeiro in an effort to determine the value of such vacines for the future field experiments in South America. Brazilian cattle, pigs and sheep were vaccinated with conventional formaldehyde-inactivated aluminum hydroxide gel-saponin adjuvanted FMD vaccines or with vaccines inactivated with AEI and emulsified with incomplete Freund’s adjuvant. Antibody development and the degree of immunity of the animals at various times after vaccination and revaccination with two vaccines were compared.
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Influence of the degree of dispersion in the aqueous phase on the immunogenicity of oil-adjuvanted foot-and-mouth disease vaccine Augé de Mello, P; Costa, KF; Fernandez, AA; Sutmöller, P; Pollak, A; Millán, A (Rio de Janeiro, PAHO, 1980)Both primary emulsion (water-in-oil) and double emulsion (water-in-oil-water) foot-and-mouth disease vaccines with different viscosities produced exellent persistent levels of neutralizing antibodies. The degree of dispersion ...
Field application of inactivated oil adjuvanted Foot-and-Mouth disease virus vaccine: vaccination and revaccination of young cattle Augé de Mello, P; Astudillo, V; Campos Garcia, JT; Gomes, I (Rio de Janeiro, PAHO, 1975)[Introduction] This paper describes the results of antibody studies after the vaccination and revaccination of young cattle with oil adjuvanted AEI inactivated FMD virus vaccines. The immune response of a group of these ...
Augé de Mello, P; Gomes, I (Rio de Janeiro, OPS, 1977)En el presente trabajo se compara la respuesta anamnéstica así como la duración de la inmunidad de tres vacunas antiaftosas inactivadas: una c on adyuvante oleoso; la segunda con hidróxido de aluminio-saponina y la tercera ...