Vaccines against foot-and-mouth disease in virus produced in cell cultures with bovine serum treated with polyethyeneglycol (PEG)
Abstract
Barteling (4) described the use of serum from cattle vaccinated against foot-and-mouth disease (FMD), from which antibodies and other factors which inhibit the replication of virus had been removed by precipitation with PEG. The author used serum in varying concentrations in culture medium to grow BHK-21 cells in suspension and found that is effect on promoting cell growth was nearly equal to similar serum without PEG treatment. He also reported that it was possible to inoculate virus in cell grown in culture medium. This latter method simplifies the process of antigen production (4).
Translated title
Vacunas contra la fiebre aftosa con virus producido en cultivos celulares con suero bovino tratado por polietilenglicol (PEG)
Subject
Citation
Abaracón D, Giacometti H. Vaccines against foot-and-mouth disease in virus produced in cell cultures with bovine serum treated with polyethyeneglycol (PEG). Bol Cent Panam Fiebre Aftosa. 1976; 21-22: 49-53.
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