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dc.contributor.authorLombardi, Clovises_ES
dc.contributor.authorSilva Pedrazzani, Elisetees_ES
dc.contributor.authorPedrazzani, Joao Carloses_ES
dc.contributor.authorFerreira Filho, Pedroes_ES
dc.contributor.authorZicker, Fabioes_ES
dc.date.accessioned2016
dc.date.available2016
dc.date.issued1996es_ES
dc.identifier.urihttps://iris.paho.org/handle/10665.2/27760
dc.description.abstractThe case-control study reported here evaluated the protective effect of BCG vacine against leprosy in Sao Paulo, Brazil. Seventy-eight patients under age 16 who had been diagnosed as having leprosy (cases) and 385 healthy individuals (controls) were selected and matched by sex, age, place of residence, and type of exposure to leprosy (intradomiciliary or extradomiciliary). The cases were draw from an active patient registry and from a group of new leprosy cases treated at 50 health centers in the cities of Bauru and Ribeirao Preto in the state of Sao Paulo. In order to estimate the protective effect of BCG, the prevalences of BCG scars in cases and controls were compared. The presence of one or more scars was associated with an estimated protective efficacy of 90 percent (95 percent confidence interval: 78 percent to 96 percent). Stratified analysis by age group, sex, socieconomic level, and clinical form of the disease revealed no significant differences in the protection provided by the vaccine, However, it seems clear that more data will be needed in order to accurately assess the true relevance of BCG for leprosy control programs (AU)en_US
dc.description.abstractThis article was also published in Spanish in the Bol. Ofic. Sanit. Panam. Vol. 119(5):415-22, 1995en_US
dc.relation.ispartofseriesBulletin of the Pan American Health Organization (PAHO);30(1),mar. 1996en_US
dc.subjectBCG Vaccinees_ES
dc.subjectLeprosyes_ES
dc.subjectCase-Control Studieses_ES
dc.subjectBrazilen_US
dc.titleProtective efficacy of BCG against leprosy in Sao Pauloes_ES
dc.typeJournal articlesen_US
dc.rights.holderPan American Health Organizationen_US


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