• español
    • English
    • português
  • English 
    • español
    • English
    • português
  • IRIS PAHO Home
  • PAHO website
  • Indexes
  • All Collections
  • About IRIS
  • Institutional Memory
  • Contact
JavaScript is disabled for your browser. Some features of this site may not work without it.
View Item 
  •   IRIS PAHO Home
  • 1.PAHO Headquarters / Sede de la OPS
  • Scientific Journals and Newsletters / Revistas Científicas y Boletines
  • Pan American Journal of Public Health
  • View Item
  •   IRIS PAHO Home
  • 1.PAHO Headquarters / Sede de la OPS
  • Scientific Journals and Newsletters / Revistas Científicas y Boletines
  • Pan American Journal of Public Health
  • View Item

Tratamiento colectivo con pirimetamina y primaquina para erradicar la malaria en Sambú, Panamá

Thumbnail
View/Open
v70n3p226.pdf (699.2Kb)
Date
s.d.
1971
Author
Comer, R. D
Young, M. D
Johnson, C. M
Babione, R. W
Metadata
Show full item record
Abstract
Pyrimethamine and primaquine were distributed house-to-house, every two weeks, for a two-year period. The last insecticide spraying of the study area took place 10 months before drug distribution began. No vector control measures were operative during the period of drug distribution. As a result, the malaria prevalence which was 17.4 per cent at the beginning of the trial, dropped to 2.4 per cent in eight weeks and to about 1 per cent in another eight weeks and persisted at the latter level for the remainder of the 49 bi-weekly cycle trial. Clinical malaria disappeared
 
Although P. vivax malaria disappeared from the study area for 32 weeks in the second year of trial, transmission of P. falciparum malaria was greatly reduced but never completely eliminated
 
Parasite importation by visitors and new settlers was a constant problem. About 2.1 per cent of all new persons encountered in the area had malaria when first seen
 
No side effects of suficient severity to prevent taking the drug combination in subsequent cycles occurred, except for complaints of headache and nausea which were ascribed to the drug
 
Malaria prevalence in the study area decreased about 94 per cent while other areas in the Republic of Panama and the Canal Zone experienced an increased prevalence during the first year of the study(AU)
 
Translated title
Mass drug trial of pyrimethamine and primaquine for the eradication of malaria en Sambu, Republic of Panama
Series
Boletín de la Oficina Sanitaria Panamericana (OSP);70(3),mar. 1971
Subject
Malária; Malária; Pirimetamina; Combinação de Medicamentos; Antimaláricos; Panamá
URI
https://iris.paho.org/handle/10665.2/15252
Collections
  • Pan American Journal of Public Health

Related items

Showing items related by title, author, creator and subject.

  • Thumbnail

    Clinical trials on drug repositioning for COVID-19 treatment 

    Rosa, Sandro G. Viveiros; Santos, Wilson C. (2020-03)
    [ABSTRACT]. The World Health Organization (WHO) was informed on December 2019 about a coronavirus pneumonia outbreak in Wuhan, Hubei province (China). Subsequently, on March 12, 2020, 125,048 cases and 4,614 deaths were ...
  • Thumbnail

    Prioridades da pesquisa clínica com medicamentos no Brasil e as doenças da pobreza 

    Santana, Rafael Santos; Leite, Silvana Nair (2016-11)
    Objetivo. Identificar os ensaios clínicos com medicamentos realizados no Brasil entre 2012 e 2015, com destaque para os que envolvem doenças da pobreza. Método. Foram pesquisados os repositórios de ensaios clínicos ReBEC ...
  • Thumbnail

    National vitamin A survey in Panama 

    Caballero, Eira; Rivera, Gloria; Nelson, David P (1996)
    The prevalence of vitamin A deficiency in a nationally representative sample of children 12-59 months old in Panama was assessed using serum retinol levels and dietary indicators. The median serum retinol level found was ...

Browse

All of IRIS PAHOCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsSeries TitleType of materialLanguageCategoryTechnical Unit/Country OfficeThis CollectionBy Issue DateAuthorsTitlesSubjectsSeries TitleType of materialLanguageCategoryTechnical Unit/Country Office

Statistics

View Usage Statistics

Pan American Health Organization
World Health Organization. Regional Office for the Americas
525 Twenty-third Street, N.W., Washington, D.C. 20037, United States of America
Tel.: +1 (202) 974-3000 Fax: +1 (202) 974-3663
email: libraryhq@paho.org

Links

  • PAHO Featured Publications
  • WHO Digital Library (IRIS)
  • Virtual Health Library (VHL)
  • Global Index Medicus (GIM)