First reported enterovirus D68 infection in pediatric patients from the Caribbean region: evidence of spread from the U.S. outbreak
Date
2017Author
Metadata
Show full item recordAbstract
The 2014 enterovirus D68 (EV-D68) outbreak in the United States raised concerns about the introduction of the virus in the Caribbean region. The objective of this study was to provide rapid evidence of the introduction of EV-D68 strains in the Caribbean region during the 2014 outbreak in the United States, using a relatively simple phylogenetic approach. From October 2014 to May 2015, four EV-D68 cases from two countries (Bermuda and Dominica) were detected at the regional referral laboratory at the Caribbean Public Health Agency (Port of Spain, Trinidad and Tobago) based on molecular testing of respiratory specimens. All cases were children presenting to hospitals with moderate respiratory distress. No cases of acute flaccid paralysis were detected. Phylogenetic analysis of the Caribbean strains showed more than 99% similarity with the 2014 U.S.-outbreak strain, providing evidence of the introduction and circulation of the virus in the region. El brote de enterovirus D68 (EV-D68) registrado en el 2014 en los Estados Unidos suscitó preocupación acerca de la introducción del virus en el Caribe. El objetivo de este estudio fue aportar pruebas rápidas, mediante la adopción de un enfoque filogénico relativamente sencillo, de que durante ese brote ingresaron en el Caribe cepas del EV-D68. Entre octubre del 2014 y mayo del 2015, el laboratorio regional de referencia ubicado en el Organismo de Salud Pública del Caribe (Puerto España, Trinidad y Tabago) detectó cuatro casos de EV-D68 provenientes de dos países (Bermudas y Dominica) mediante el análisis molecular de muestras respiratorias. Todos los casos correspondían a niños que acudieron al hospital con dificultad respiratoria moderada. No se detectó ningún caso de parálisis flácida aguda. El análisis filogénico de las cepas encontradas en el Caribe demostró una semejanza superior al 99 % con la cepa responsable del brote del 2014 en los Estados Unidos, lo que demuestra la introducción y la circulación del virus en la región.
Translated title
Primeros casos notificados en el Caribe de infección por enterovirus D68 en pacientes pediátricos: pruebas de la propagación del brote de los Estados Unidos
Subject
Category of PAHO Strategic Plan 2014-2019
Citation
Nathaniel S, Ahmed S, Wilson J, Gutierrez C, Chadee DD, Olowokure B, et al. First reported enterovirus D68 infection in pediatric patients from the Caribbean region: evidence of spread from the U.S. outbreak. Rev Panam Salud Publica. 2017;41:e11.
Collections
Related items
Showing items related by title, author, creator and subject.
-
Pan American Health Organization; Health Emergencies (PHE) (PAHOUnited StatesWashington, D.C., 2023)[WEEKLY SUMMARY]. North America: Influenza virus activity decreased throughout the sub-region, with the predominance of influenza A(H1N1)pdm09. Influenza A(H3N2)pdm09 and B/Victoria co-circulated. SARS-CoV-2 circulates at ...
-
Pan American Health Organization; Health Emergencies (PHE) (PAHOUnited StatesWashington, D.C., 2020)In 2020, between epidemiological week (EW)1 and EW 41, 9 countries in the Region of the Americas have reported a total of 8,479 confirmed cases of measles, including 8 deaths: Argentina (61 cases including 1 death), Bolivia ...
-
Pan American Health Organization; Health Emergencies (PHE) (PAHOUnited StatesWashington, D.C., 2023)[WEEKLY SUMMARY]. North America: Influenza activity was moderate, although decreasing in the subregion, with the predominance of influenza A(H3N2) and co-circulation of A(H1N1)pdm09 and B/Victoria. The SARS-CoV-2 activity ...