Aislamiento e identificación de virus de fiebre aftosa procedente de vesículas en la epidermis de un ser humano
1. A cytopathogenic agent for bovine kidney cells isolated from hand vesicles of a human being2. This agent is pathogenic for bovine kidney cells in vitro, guinea pigs and suckling mice3. This agent belongs immunologically to the "O" type foot and mouth disease virusDiscussionIn spite of the fact that the patient has been working for over 10 years with foot and mouth disease viral materials, she never presented before similar symptoms. A search for heterologous antibodies produced by inapparent or subclinical infections was made. Neither the acute nor the convalescent sera, when diluted 1:8, revealed the presence of antibodies against A and C type foot and mouth virusesThis brief paper shows the possible existence in nature of some peculiar foot and mouth virus strains, which, in some special circumstances, could infect manConclusionsThe fluid from a hand vesicle of a human produced destruction in bovine kidney cultural cells. In this way a cytopathogenic agent has been isolated in vitro. The specific inhibition of cellular destruction by this agent in the presence of "O" type hyperimmune guinea pig serum proves that this agent belongs immunologically to the "O" type foot and mouth disease virusIt is the first time that a foot and mouth disease virus from a human has been isolated in bovine kidney cells cultured in vitro(AU)Este trabajo se publica simultáneamente en el Canadian Veterinary Journal
Isolation and identification of foot and mouth disease virus from skin vesicles in a human being
Showing items related by title, author, creator and subject.
Vaccines against foot-and-mouth disease in virus produced in cell cultures with bovine serum treated with polyethyeneglycol (PEG) Pan American Health Organization; Pan American Foot and Mouth Disease Center (Rio de Janeiro, PAHO, 1976)Barteling (4) described the use of serum from cattle vaccinated against foot-and-mouth disease (FMD), from which antibodies and other factors which inhibit the replication of virus had been removed by precipitation with ...