Un estudio de la OMS relativo a los esquemas de tratamiento de la sifilis temprana, en uso en todo el mundo
Ten years have elapsed since penicillin was introduced in the treatment of syphilis. In order to appraise recent trends in syphilotherapy in the world, WHO carried out a detailed study of treatment practices in early syphilis. A questionnaire was circulated to leading venereologists and clinics in the world, and 277 replies were received from 55 countries giving particulars of 294 schedulesA total of 65.3 per cent of the participants used penicillin alone and 28.9 per cent used it in combination with other drugs. In North America all clinics relied solely on penicillin as against 52.2 per cent in Europe; and procaine penicillin G in oil with aluminum monostearate (PAM) was used in 91 per cent of clinics in the Americas and Asia and in 60.6 per cent of European clinics. The most common dosage of penicillin in all stages of early syphilis was 4.8-6.0 million units; but appreciably larger doses were used in Europe than elsewhere, some 39.4 per cent of schedules using 10.8 million units or more. There were single instances of 36 million units being given. Consolidation treatment was given in none of the North American clinics; seldom in Asia; by about one-third of the participants in Central and South America; and, for secondary syphilis, in 59 per cent of European schedulesThis study shows that with intensive treatment with PAM the saving in drug cost to clinics over the classical courses ... (AU)Publicado en inglés en el WHO 10(4):579, 1954
A WHO estudy of treatment schedules for early syphilis in use throughout the world
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Guidance on Syphilis Testing in Latin America and the Caribbean: Improving Uptake, Interpretation, and Quality of Testing in Different Clinical Settings Pan American Health Organization (Washington, D.C, PAHO, 2015)[Background]: In 2007, the World Health Organization (WHO), in collaboration with global partners, launched a global initiative for the elimination of congenital syphilis as a public health problem. Congenital syphilis ...
Comparative effectiveness of single and dual rapid diagnostic tests for syphilis and HIV in antenatal care services in Colombia Gaitán-Duarte, Hernando Guillermo; Newman, Lori; Laverty, Maura; Habib, Ndema Abu; González-Gordon, Lina María; Ángel-Müller, Edith; Abella, Catleya; Barros, Esther Cristina; Rincón, Carlos; Caicedo, Sidia; Gómez, Bertha; Pérez, Freddy (2016-12)Objective. To assess the effectiveness of a dual rapid test compared to a single rapid test for syphilis and HIV screening. Methods. A cluster-randomized open-label clinical trial was performed in 12 public antenatal ...
Oxacillin disk diffusion testing for the prediction of penicillin resistance in Streptococcus pneumoniae Horna, Gertrudis; Molero, María L.; Benites, Liliana; Roman, Sigri; Carbajal, Luz; Mercado, Erik; Castillo, María E.; Zerpa, Rito; Chaparro, Eduardo; Hernandez, Roger; Silva, Wilda; Campos, Francisco; Saenz, Andy; Reyes, Isabel; Villalobos, Alex; Ochoa, Theresa J. (2016-07)Objective. To 1) describe the correlation between the zones of inhibition in 1-μg oxacillin disk diffusion (ODD) tests and penicillin and ceftriaxone minimum inhibitory concentrations (MICs) of meningeal and non-meningeal ...